I have been having issues with Orbus crashing a lot for me. It tends to happen 10-25ish minutes into gameplay and does not appear to matter what I am doing.
I was directed to an older thread to try some things (Megathread: Frequent Crashes).
So far I have already updated (Windows7, Steam, Vive software, GPU drivers), had Steam verify the game files, checked to make sure I am not in the SteamVR beta nor the Orbus Beta branches, confirmed supersampling is set to 1.0, tried the three connection methods on the login screen.
So far I have not experienced this crash with other games.
System: Intel i7-4820K @3.9GHz, 16GB DDR3 2133, GTX1080TI, Vive
Temps around crash time: CPU ~45, GPU ~68
Crash log emailed